Expertise at Chang Gung System

Ke, Po-Yuan ,Ph.D.
Institution: Chang Gung University
Position: Assistant Professor
Department: Department of Biochemistry & Molecular Biology
Address: No. 259 Wen-Hwa 1st Road, Kwei-Shan Tao-Yuan, Taiwan 33302, R.O.C
Tel: +886-3-2118800 ext 5115
E-mail: pyke0324@mail.cgu.edu.tw

Focus of Interest:
  • Biochemistry and Molecular Biology – Medicine
  • Infectious Diseases
  • Microbiology

Fulltime Employment:
  • Assistant Professor, Department of Biochemistry & Molecular Biology, Chang Gung University 2012/2~present

Education:
  • Ph.D. Graduate Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University

Honors and Awards:
  • 2003 Excellent Publication Award for Graduate Student, National Taiwan University, College of Medicine
  • 2003 International Conference Travel Award, The Chinese Society of Cell and Molecular Biology
  • 2004 Dr. Chien-Tien Hsu Award in 12th Symposium on Recent Advances in Cellular and Molecular Biology
  • 2004 Outstanding Student Award in Academy, National Taiwan University
  • 2005 Post-doctoral Fellowship Award, National Health Research Institute
  • 2005 The President Award in Medicine and Technology, Tien-Te Lee Biomedical Foundation, Yung Shin PHARM. IND. CO., LTD
  • 2009 Poster Award, 17th Symposium on Recent Advances in Cellular and Molecular Biology
  • 2010 Poster Award, 18th Symposium on Recent Advances in Cellular and Molecular Biology
  • 2010 Research Article Competition Award for Post-Doctoral Research Fellow, Institution of Biomedical Sciences, Academia Sinica
  • 2010 International Travel Fellowship and Invited Oral Presentation Award, 17th International Meeting on Hepatitis C Virus and Related Viruses
  • 2011 Outstanding Paper Award on hepatitis C virus research of Liver Disease Prevention & Treatment Research Foundation, Taiwan, R.O.C.

Selected Main Publications:
  1. Autophagy in hepatitis C virus-host interactions: Potential roles and therapeutic targets for liver-associated diseases. Ke, P.Y. and Chen, S,S.L. World Journal of Gastroenterology 20: 5773-5793, 2014
  2. Active RNA replication of hepatitis C virus downregulates CD81 expression. Ke, P.Y. and Chen, S.S.L. PLoS ONE8: e54866, 2013.
  3. Autophagy: a new guardian of HCV against innate immune response. Ke, P.Y. and Chen, S.S.L. Autophagy 7: 533-535, 2011.
  4. Activation of the unfolded protein response and autophagy after hepatitis C virus infection suppresses innate antiviral immunity in vitro. Ke, P.Y. and Chen, S.S.L. Journal of Clinical Investigation 121: 37-56, 2011.
  5. Control of dTTP pool size by anaphase promoting complex/cyclosome is essential for the maintenance of genetic stability. Ke, P.Y., Kuo, Y.Y., Hu, C.M., and Chang, Z.F. Genes & Development19: 1920-1933, 2005.


All Publications List

Board Certification :

  • Peer Reviewer: Autophagy; Viruses; Apoptosis