Expertise at Chang Gung System

Chih-Wei Yang ,M.D.
Institution: Linkou chang gung memorial hospital / Chang gung university
Position: Professor; Dean, College of Medicine
Department: Division of Nephrology; College of Medicine
Address: No 5, Fu Hsing Street, Kuei Shan, Taoyuan County, Taiwan, R.O.C. Linkou Chang Gung Memorial Hospital
Tel: +886-3-328-1200 ext.2506 Fax: +886-3-3285905
E-mail: cwyang@ms1.hinet.net

Focus of Interest :
  • Immunology
  • Infectious Diseases
  • Medicine, General & Internal
  • Urology & Nephrology
  • Hemodialysis

Employment Records :
Dec.1990- Research Fellow Renal Cell Biology Section
Dec.1991 NIDDK, National Institutes of Health, USA
Dec.1991- Visiting Associate Renal Cell Biology Section
Nov.1994 NIDDK, National Institutes of Health, USA
July 1994-Nov 1999 Associate Professor Division of Nephrology Chang Gung Memorial Hospital, Taiwan
May 1996-Aug. 2002 Associate Professor ChangGung University Medical School, Taiwan
July 1998- Adjunct Associate Kaohsiung Medical School Post-graduate
June 1999 Professor Medical Research Institute, Taiwan
Dec. 1999-Present Professor Department of Nephrology Chang Gung Memorial Hospital, Taiwan
Aug. 2002-Present Professor Chang Gung University Medical School, Taiwan
Aug. 2004- Adjunct Professor Taipei University Medical School, Present Taiwan
Sep. 2004-Present Director Kidney Research Center, Chang Gung Memorial Hospital, LinKou, Taiwan
Sep. 2005- Chairman Department of Medical Research, Chang Gung 2009 Memorial Hospital, LinKou, Taiwan
July. 2007- Vice Chairman Research & Development Committee, Dec 2012 Chang Gung Medical Foundation, Taiwan
August 2011-Present Dean College of Medicine, Chang Gung University, Taiwan

Education:
Taipei Medical College, Taipei, Taiwan


Honor and Awards :
1. Award of Bioscience Research, National Science Council, Taiwan, 1998
2. Award of Bioscience Research, National Science Council, Taiwan, 1999
3. Award of Bioscience Research, National Science Council, Taiwan, 2000
4. Award of Bioscience Research, National Science Council, Taiwan, 2001
5. Outstanding Award of Bioscience Research, National Science Council, Taiwan, 2008
6. Outstanding Research Award, ChangGungUniversity, 2009
7. Outstanding Biomedical Research Award, Tien-Derh Li Foundation, 2010

Selected Publications :

  1. Yang CW*, Wu MS, Pan MJ, Hong JJ, Yu CC, Vandewalle A, Huang CC.

    Leptospira outer membrane protein activates nf-kappa b and downstream genes expressed in medullary thick ascending limb cells. J Am Soc Nephrol.,2000, 11(11), 2017-2026.

  2. Yang CW*, Wu MS, Pan MJ, Hsieh WJ, Vandewalle A, Huang CC The leptospira outer membrane protein lipl32 induces tubulointerstitial nephritis-mediated gene expression in mouse proximal tubule cells. J Am Soc Nephrol,2002, 13, 2037-2045.

  3. Yang CW*, Hung CC, Wu MS, Tian YC, Chang TZ, Pan MJ, Vadewalle A

    Toll-like receptor 2 mediates early inflammation by leptospiral outer membrane proteins in proximal tubule cells. Kidney Int,2006, 69, 815–822.

  4. Tian YC, Chen YC, Hung CC, Chang CT, Wu MS, Phillips AO, Yang CW*.

    Leptospiral outer membrane protein induces extracellular matrix accumulation through a tgf-{beta}1/smad-dependent pathway.

  5. J Am Soc Nephrol,2006, 17(10): 2792-8.

    Yang CW*. Leptospirosis renal disease: understanding the initiation by toll-like receptors .Kidney Int,2007, 72(8):918-25.


Full Publication List

Board Certification / Professional Affiliations:
Executive Committee Member, International Society of Nephrology

Ongoing projects:
1) Innate Immunity and Leptospira Associated Renal Fibrosis： Genomic, Structural and Functional Mechanistic Study
2) Panthogenic mechanism of leptospira species based on the interaction of leptospires and host cells