Expertise at Chang Gung System

Sien-Hung Yang ,M.D. Ph.D.
Intitution: Chang Gung Memorial Hospital / Chang Gung University
Position: Director/Associate professor
Department: Traditional Chinese Medicine
Mail Address: 123, Ding-Hu Road, Kweishan, Taoyuan, Taiwan
Tel: +886-3-319-6200 ext.2611 Fax: +886-3-3298995
E-mail: dryang@adm.cgmh.org.tw

Focus of Interest:
  • Allergic rhinitis
  • Asthma
  • Atopic dermatitis
  • Urticaria
  • CD4+ T lymphocytes
  • Dendritic Cells

Research Summary
Allergic diseases are important in Taiwan due to its high prevalence, from our previous research, we found the Chinese medicine is beneficial for the treatment of allergic diseases due to its immuno-modulated effects. We are interest to study and compare the mechanism and pathway of Chinese medicine from western medicine done in the treatment of allergic diseases. There are two major goals of my study including, clinical trial for the evaluation the effects of Chinese medicine on the treatment of allergic diseases and the modification of molecular mechanisms of Dendritic cells and CD4+ T cells under the treatment of Chinese medicine.  

Employment Records :

 ◎ 1987 – 1990 Resident doctor, Department of Internal Medicine, Cathay General Hospital, Taiwan
 ◎ 1990 – 1996 Visiting staff, Yang’s Traditional Chinese Medicine Clinical, Taiwan
 ◎ 1996 – Present  Visiting staff, Chang Gung Memorial Hospital, Linkuo, Taiwan
 ◎ 2001 – Present  Associate Professor, School of Traditional Chinese Medicine, Chung-Gung University, Kweishan, Taiwan

Education:

 》 1978- 1985 Bachelor, School of Chinese medicine, China Medical University, Taiwan
 》 1994- 1996 Master, Institute of Traditional Medicine, School of Medicine, National Yang-Ming University, Taiwan
 》 1996- 2002 PhD, Institute of Clinical Medicine, School of Medicine, National Yang-Ming University, Taiwan

Selected Publications:
  1. Yang SH*, Yu CL. Antiinflammatory Effects of Bu-Zhong-Yi-Qi-Tang in Patients with Perennial Allergic Rhinitis. Journal of Ethopharmacology 2008,;115:104-9.
  2. Yang SH*, Yu CL, Chen YL, Chiao SL, Chen ML. Traditional Chinese medicine, Xin-yi-san, reduces nasal symptoms of patients with perennial allergic rhinitis by its diverse immunomodulatory effects. International Immunopharmacology 2010,10:951-8.
  3. Yang SH*, Chen HY, Lin YS, Chen YC. The Exploration of Disease Pattern, Zheng, For Differentiation of Allergic Rhinitis in 1 Traditional Chinese Medicine Practice. Evidence-Based Complementary and Alternative Medicine 2012 Article ID 521780, 7 pages doi:10.1155/2012/521780
  4. Lin YH, ChenYC, Hu S, Chen HY, Chen JL, Yang SH*. Identifying core herbal treatments for urticaria using Taiwan’s nationwide prescription database. Journal of Ethnopharmacology 2013 ,148:556-62.
  5. Yang SH*, Yu CL, Chen HY, Lin YH. A Commonly Used Chinese Herbal Formula, Shu-Jing-Hwo-Shiee-Tang, Potentiates Anticoagulant Activity of Warfarin in a Rabbit Model. Molecules2013, 18: 11712-11723
Full Publication List

Honor and Awards:

2004   Medical Research Award of  ”The New Century Health Care Promotion Foundation”

Ongoing Projects:
1.Study the intracellular inhibited signaling controlled on human CD4+ T lymphocytes in the patients of perennial allergic rhinitis treatment by mixed formula of Chinese medicine.
2. Study the effects of Chinese herbal medicine on chronic urticaria: a randomized, double-blind, placebo-controlled clinical trial.
3. Construction of cancer diseases in the integrated treatment of both traditional Chinese medicine and Western medicine cooperation in the conventional ward treatment and efficacy evaluation

Board Certification / Professional Affiliations:
Department of Health, the National Health Insurance Council for review experts dispute.