Expertise at Chang Gung System

Chia-Rui Shen, Ph.D.
Intitution: Chang Gung University
Position: Associate Professor
Department: Medical Biotechnology and Laboratory Science
Mail Address: 259 Wen-Hua 1st Road, Kweishan, Taoyuan 333, Taiwan.
Tel: +886-3-211-8800 ext.5200
E-mail: crshen@mail.cgu.edu.tw

Focus of Interest:
  • Immunotherapy
  • Vaccine
  • Immunoregulation
  • Autoimmune disease
  • Molecular Imaging
  • Biomaterials
Employment Records :
1993-1994: Teaching Assistant, Department of Medical Technology, National Cheng Kung University
2000-2010: Assistant Professor, Department of Medical Biotechnology and Laboratory Science, Chang Gung University
2010–Present :Associate Professor Department of Medical Biotechnology and Laboratory Science, Chang Gung University

Education:

1989-1993 BSc, Medical Technology,   National Cheng Kung University

1995-1998 PhD, Immunology, University of Bristol, United Kingdom

1998-2000 Postdoc, Vaccine development, Institute of Biomedical Sciences, Academia Sinica

Selected Publications:
1. Shen CR, Yang WC, Chen HW. The fate of regulatory T cells: survival or apoptosis. Cellular & Molecular Immunology 2013 doi:10 1038/cmi.2013.49.
2. Chen YS, Liu CL, Lee MH, Chen HW, Shen CR (correspondence). The role of Tc17 in cancer immunity and clinical associations. J Biomed Lab Sci 2013 Sep; 25(3): 77-83.
3. Hwang YS, Chiang PR, Hong WH, Chiao CC, Chu IM, Hsiue GH, Shen CR (correspondence). Study in vivo intraocular biocompatibility of in situ gelation hydrogels: Poly (2-ethyl oxazoline)- block- poly ( - caprolactone)- block- poly (2-ethyloxazoline) Copolymer, Matrigel and Pluronic F127. PLoS One 2013 (7): e67495.
4. Tsai ZT, Tsai FJ, Yang WC, Wang JF, Liu CL, Shen CR (correspondence), Yen TC. Preparation and characterization of ferrofluid stabilized with biocompatible chitosan and dextran sulfate hybrid biopolymer as a potential MRI T2 contrast agent. Mar Drugs 2012; 10(11), 2403-2414. (CHEMISTRY, MEDICINAL, 10.17%)
5. Tsai JP, Lee MH, Hsu SC, Chen MY, Liu SJ, Chang JT, Liao CT, Cheng AJ, Chong P, Shen CR (correspondence), Chen HW. CD4+ T cells disarm or delete cytotoxic T lymphocytes under IL-17-polarizing conditions. J Immunol 2012 189:1671-1679

Honor and Awards:
  • 1990 Outstanding Youth Awards, National Cheng Kung University.
  • 1996 Overseas Research Studentship, 96008007, Universities and Colleges in the U.K.
  • 1999 Postdoctoral Fellowship, Academia Sinica.
  • 2008- Council Member, Taiwan Society of Chitin and Chitosan
  • 2012- Council Member, Chinese Society of Immunology.
  • 2013 Visiting Scholarship, Academia Sinica.
Research Source:
Mouse strains: B6, B10, BALB/c, NZB
Cell lines: 3T3, RAW, HEK293, THP-1…etc.
Special technology: Few cell QPCR, Immunosorting, Gene therapy, Imaging…etc.