Expertise at Chang Gung System

Hong Chang , M.D.
Institution: Linkou Chang Gung Memorial Hospital / Chang Gung University
Position: Physician / Assistant professor
Department: Hematology
Address: No.5, Fusing St., Gueishan Township, Taoyuan County 333, Taiwan (R.O.C.)
Tel: +886-3-3281200
E-mail: horng@cgmh.org.tw

Focus of Interest:
  • Hematology

Employment Records:
2014-present, Assistant professor, Chang Gung University
2007-2008: Research fellow/visiting scholar in Center of Platelet Function Studies, University of Massachusetts Medical School
2003-present: Attending physician Division of Hematology, CGMH
2001-2003: Fellow/Chief resident, Division of Hematology, CGMH
1998-2001 Resident, Department of Internal Medicine, CGMH
1995-1996: Medical Intern, Chang Gung Memorial Hospital (CGMH)

Education:
Taipei Medical College, Taipei, Taiwan

Honor and Awards:
2014, 2009 Award for Distinguished Scientific Research, The Hematology Society of Taiwan
2013 Award for Outstanding Scientific Paper for Young Researcher, The Hematology Society of Taiwan
2013, 2009, 2006 Best Abstract Award, The Hematology Society of Taiwan
2012 Roche Award for Distinguished Lymph-related Hematologic Disease Research, The Hematology Society of Taiwan

Selected Publications:
  1. Chang H, Yanachkov IB, Michelson AD, Li Y, Barnard MR, Wright GE, Frelinger AL 3rd. Agonist and antagonist effects of diadenosine tetraphosphate, a platelet dense granule constituent, on platelet P2Y1, P2Y12 and P2X1 receptors. Thromb Res 2010;125:159–165
  2. Chang H , Hung YS, Lin TL, Wang PN, Kuo MC, Tang TC, Wu JH, Dunn P, Shih LY. Primary bone marrow diffuse large B-cell lymphoma: a case series and review. Annals of Hematology 2011;90:791-6
  3. Chang H, I.B. Yanachkov, E.J. Dix, Y.F. Li, M. R. Barnard, G. E. Wright, A.D. Michelson, Andrew L. Frelinger III: Modified diadenosine tetraphosphates with dual specificity for P2Y1 and P2Y12 are potent antagonists of ADP-induced platelet activation. J Thromb Haemost 2012;10:2573-80
  4. Chang H, Yanachkov I, Dix EJ et al. Antiplatelet activity, P2Y₁ and P2Y₁₂ inhibition, and metabolism in plasma of stereoisomers of diadenosine 5',5'''-P¹,P⁴-dithio-P²,P³- chloromethylenetetraphosphate. PLoS One 2014 9:e94780
  5. Chang H, Tang TC: Surgical site spread of skeletal diffuse large b cell lymphoma. J Clin Oncol 2013 Mar 20;31:e141-3

 


Board Certification/Professional Affiliations:
Hematology, Taiwan
Blood and BM Transplantation, Taiwan
Internal Medicine, Taiwan

Ongoing Projects:
Translational research for improving cancer patient survival in Taiwan: A multiple center approach (Blood cancer: adult acute myeloid leukemia) (2014.01.01-2017.12.31, Co-PI, MOHW)
A retrospective, multi-facet analysis of infectious disease profiles in patients with leukemia and lymphoma in Chang Gung Memorial Hospital in Linkou (2013.10.01-2016.09.30, PI, CGMH)