Expertise at Chang Gung System

Pi, Hai-Wei ,Ph.D.
Institution: Chang Gung University
Position: Associate professor
Department: Department of Biomedical Science
Address: No.259, Wenhua 1st Rd., Guishan Dist., Taoyuan City 33302, Taiwan (R.O.C.)
Tel: +886-3-3281200 ext.3361
E-mail: haiwei@mail.cgu.edu.tw

Focus of Interest:
  • Genetics
  • Molecular Biology
  • Molecular & Cell Biology
  • Molecular Biology
  • Neurosciences
  • Stem cell

Fulltime Employment:
  • 2014/08-now
    Chang Gung University Department of Biomedical Sciences Associate professor
  • 2004/08-2014/07
    Chang Gung University Department of Biomedical Sciences Assistantprofessor
  • 2008/11-2009/05
    Stanford University Department of Biology Guest Assistant Professor
  • 2003/08-2004/07
    Tunghai University Department of Biologya Assistant professor
  • 1997-2003
    Academia SinicaInstitute of Molecular Biology Postdoctoral researcher

Education:
  • Ph.D., Department of Biochemistry and Cell Biology, State University of New York Stony Brook, USA

Honors and Awards:
  • Jan. 2002-July. 2003 National Science Council Post-doctoral Scholar (Co-director for the NSC grants NSC91-2311-B-001-066, NSC92-2311-B-001-032).
  • Jan. 2000-Dec.2001 Academia Sinica Post-doctoral Scholar
  • Jan. 1988 Book Coupon Award form National Taiwan University

Selected Main Publications:
  1. Yi Chieh Chang, Hsin Tu, Jing-Yi Chen, Ching-Chin Chang, Shu Yuan Yang, Haiwei Pi* (2019) Reproduction disrupts stem cell homeostasis in testes of aged male Drosophila via an induced microenvironment. PLoS Genet15 (7): e1008062. (Published on July, 11)This paper is highlighted by an accompanying Perspective article “ Irreversible effects of youthful choices in aged adults” in PLoS Genetics.
  2. Yi-Chun Huang, Yu-Nung Lu, June-Tai Wu, Cheng-Ting Chien*,Haiwei Pi.*(2014) The COP9 Signalosome Converts Temporal Hormone Signaling to Spatial Restriction on Neural Competence. PLOS Genetics. 10(11):e1004760.
  3. Hsiao, Y.-L, Chen, Y.-J., Chang, Y.-J., Yeh H.-F, Huang Y,-C., and Pi, H.*(2014) Proneural proteins Achaete and Scute associate with nuclear actin to promote external sensory organ formation. Journal of Cell Science. 127:182-90.
  4. Chang Y.-J.†, Pi, H.†*, Hsieh C.-C, Fuller, MT. (2013) Smurf-mediated differential proteolysis generates dynamic BMP signaling in germline stem cells during Drosophila testis development. Developmental Biology 383(1):106-20. (†These two authors contribute equally to this work).
  5. Chang P.-J., Hsiao Y.-L., Tien A.-C., Li Y.-J., and Pi H.*(2008) Negative feedback regulation of proneural proteins controls the timing of neural precursor division. Development. 135,3021-30.

Ongoing Projects:
  1. [2016.06.01-2019.05.31] In male drosophila gonads, the JNK pathway regulates the constant molecular mechanism of cyst stem cell
  2. [2018.08.01-2019.07.31] Regulation of ribosomal biogenesis in neural precursors by bHLH proneural proteins

All Publications List