Expertise at Chang Gung System

Sebastian D. Fugmann ,Ph.D.
Institution: Chang Gung University
Position: Professor
Department: Biomedical Sciences
Address: 259 Wenhua 1st Rd, Gueishan Township, Taoyuan County 333, Taiwan (R.O.C.)
Tel: +886-3-211-8800 ext.3478
sdfugmann@mail.cgu.edu.tw

Focus of Interest:
  • Biochemistry and Molecular Biology - Medicine
  • Immunology
  • Infectious Diseases

Fulltime Employment:
  • 2004-2013 Investigator, National Institute on Aging / NIH, Baltimore, MD, USA
  • 2013- now Professor, Dept. of Biomedical Sciences, Chang Gung University, Gueishan, Taiwan

Education:
  • 1990 Vordiplom (B.Sc.), Chemistry, University of Hamburg, Germany
  • 1993 Diplom (M.Sc.), Physical Chemistry, University of Constance, Germany
  • 1998 Ph.D., Human Biology, University of Ulm, Germany
  • 1998-2004 Postdoctoral Fellow, Yale University, New Haven

Honors and Awards:
  • 1994 Predoctoral Fellowship, Deutsche Forschungsgemeinschaft (DFG), GraduiertenkollegfuerBiomolekulareMedizin, University of Ulm, Germany
  • 2001 Postdoctoral Fellowship, Irvington Institute for Immunological Research, USA

Selected Main Publications:
  1. Fugmann, S.D., Villey, I.J., Ptaszek, L.M., and D.G. Schatz, D.G. Identification of two catalytic residues in RAG1 that define a single active site within the RAG1/RAG2 protein complex.  Mol. Cell 5: 97-107, 2000.
  2. Fugmann, S.D., Messier, C., Novack, L.A., Cameron, R.A., and Rast, J.P.: An ancient evolutionary origin of the RAG1/2 gene locus.  Proc. Natl Acad. Sci. USA 103: 3728-3733, 2005.
  3. Sea Urchin Genome Sequencing Consortium (including Fugmann, S.D.): The genome of the sea urchin Strongylocentrotus purpuratus.  Science 314: 941-952, 2006.
  4. Kothapalli, N., Norton, D.D., and Fugmann, S.D.: Cutting Edge: A cis-acting DNA element targets AID-mediated sequence diversification to the chicken Ig light chain gene locus.  J. Immunol. 180: 2019-2023, 2008.  
  5. Kothapalli, N.K., Fugmanns, S.D.: Targeting of AID-mediated sequence diversification to immunoglobulin genes. Curr. Opin. Immunol. 23: 184-189, 2011.  PMCID: PMC3073656

All Publications List