Expertise at Chang Gung System

Chen, Chien-Chung ,Ph.D.
Institution: Chang Gung university
Position: Assistant Professor
Department: Department of Biomedical Sciences
Address: 259 Wen-Hwa 1st Road, Kwei-Shan, Tao-Yuan 333, Taiwan (R.O.C.)
Tel: +886-3-2118800 #3730 Fax: +886-3-2118700
E-mail: chencc@mail.cgu.edu.tw

Focus of Interest:
  • Biochemistry and Molecular Biology - Medicine
  • Nutrition & Dietetics
  • Oncology

Fulltime Employment:
  • 2008-2014 Manager of Research Projects, Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA, USA
  • 2004-2007 Post-doctoral researcher, Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA, USA. Advisor: Lewis Chodosh, M.D., Ph.D.

Education:
  • 1999-2004 Ph.D. in Pharmacology, Wayne State University, Detroit, MI, USA
  • 1993-1995 M.S. in Biochemistry, Chung Shan Medical University, Taiwan, R.O.C.
  • 1989-1993 B.S. in Medical Technology, Chung Shan Medical University, Taiwan, R.O.C.

Honors and Awards:
  • 2009 Awarded Travel Fellowship at 12th Society of Chinese Bioscientists in America International Symposium
  • 2007 Awarded for Inaugural Sanjeev Kumar Memorial Lecture at University of Pennsylvania
  • 2004 Awarded Academic and Research Accomplishments at Wayne State University

Selected Main Publications:
  1. Alvarez, J.V., Belka, G.K., Pan, T.-c., Chen, C.-C., Blankemeyer, E., Alavi, A., Karp. J., and Chodosh, L.A. (2014) Oncogene pathway activation in mammary tumors dictates [18F]-FDG-PET uptake. Cancer Research Published online first September 19, 2014; doi: 10.1158/0008-5472.CAN-14-1235.
  2. Chen, C.-C., Stairs, D.B., Boxer, R.B., Belka, G.K., Horseman, N.D., Alvarez, J.V., and Chodosh, L.A. (2012) Autocrine prolactin induced by the PTEN-Akt pathway is required for lactation initiation and provides a direct link between the Akt and Stat5 pathways. Genes Development 26:2154-2168.
  3. Chen, C.-C., Boxer, R.B., Stairs, D.B., Portacarrero, C.P., Horton, R.H., Alvarez, J.V., and Chodosh, L.A. (2010) Akt is required for Stat5 activation and mammary differentiation. Breast Cancer Research 12(5):R72. [Epub ahead of print]
  4. Chen, C.-C., and Wu, H.-Y. (2005) LeuO protein delimits the transcriptionally active and repressive domains on the bacterial chromosome. Journal of Biological Chemistry 280:15111-15121.
  5. Chen, C.-C., Chou, M.Y., Huang, C.H., Majumder, A., and Wu, H.-Y. (2005) A cis-spreading nucleoprotein filament is responsible for the gene silencing activity found in the promoter relay mechanism. Journal of Biological Chemistry 280: 5101-5112.


All Publications List