Tsai SW

Tsai, Shau-Wei ,Ph.D.
Institution: Chang Gung University
Position: Professor
Department: Institute of Biochemical and Biomedical Engineering
Address: No.259, Wen-Hwa 1st Rd., Kwei-Shan, Tao-Yuan County 333, Taiwan (R.O.C.)
Tel: +886-3-2118800-3415 Fax: +886-3-2118800-3410
E-mail: tsai@mail.cgu.edu.tw

Focus of Interest:

• Enzymatic biotransformation

Fulltime Employment:

• Department of Chemical Engineering, Cheng Kung University (1982/08 ~ 2005/07)
• Institute of Biochemical and Biomedical Engineering, Chang Gung University(1982/08 ~)

Education:

• Department of Chemical Engineering, Cheng Kung University (1982/08 ~ 2005/07)

Selected Main Publications:

1. Tsai, S. W. 2016. “Enantiopreference of Candida antarctica lipase B toward carboxylic acids: substrate models and enantioselectivity thereof,” J. Mol. Cat. B: Enzymatic, 127, 98-116.
2. Hsiao, H. T. Lin, S. Y. Tsai, S. W. 2016. “Quantitative insights and improvements of enzyme activity and stereoselectivity for CALB-catalyzed alcoholysis in two-step desymmetrization,” J. Mol. Cat. B: Enzymatic, 127, 82-88.
3. Ko, P. T., Lee, I. C., Chen, M. C., Tsai, S. W. 2015. “Polymer microneedles fabricated from PCL and PCL/PEG blends for transdermal delivery of hydrophilic compounds,” JTIChE, 51, 1-8.
4. Huang, Y. K. Tsai, S. W., 2014.“Kinetic and thermodynamic analysis of Candida antarctica lipase B-catalyzed alcoholytic resolution of (R,S)-β-butyrolactone in organic solvents,” App. Microb. Biotechnol., 98, 621-628.
5. Wu, C. H., Pen, C. W., Wang, P. Y., Tsai, S. W., 2013.“An efficient lipase-catalyzed enantioselective hydrolysis of (R,S)-azolides derived from N-protected proline, pipecolic acid, and nipecotic acid,” App. Microb. Biotechnol., 97, 1581-1587.

All Publications List

Board Certification:

• TIChE
• CCS
• BEST

Ongoing projects:

• Development of chemoenzymatic process for preparing optically pure intermediates for the preparation of antidepressant (1S,2R)-tranylcypromine and the alike (08/01/2016 ~ 07/31/2018)