專業人才

周美智 , Ph.D.
單位: 長庚大學
職稱: 長庚大學醫學院生理暨藥理學科 助理教授
聯絡地址: 桃園市龜山區文化一路259號長庚大學醫學院生理暨藥理學科
電話: 03-2118800 轉 5974 (Lab) ; 5251 (Office) 傳真: 03-2118700
E-mail: mjjou@mail.cgu.edu.tw

研究領域:
  • 藥理及生理
  • laser scanning multi-photon microscopy
  • pathophysiology of mitochondria-mediated apoptosis
  • neurodegenerative diseases (Parkinson's disease and Alzheimer's disease)
  • nano-medicine, phototoxicity and photodynamic therapy
  • mitochondrial diseases

工作經歷:
1999 ~ 2006 長庚大學 生理暨藥理學科 助理教授

學歷:
高雄醫學院藥學系學士
台灣大學藥理研究所碩士
美國羅徹斯特大學藥理學博士

殊榮:
2009: 謝承恩同學2009財團法人台灣醫學發展基金會論文指導獎
2008: 謝承恩同學2008財團法人台灣醫學發展基金會論文指導獎
2007: 2007 Edition of Who’s Who in the World, USA
2006: The American Hall of Fame by American Biographical Institute, INC., USA
2006: International Travel Grant at Biophysical Society, USA
2005: Young Investigator Award by First Annual Meeting of The American Academy of Nanomedicine (AAAM), USA
2005: Leading Scientists of the World in The Area of Mitochondria Research by International Biographical Center Headquarters in Cambridge, England
2005: American Academy of Nanomedicine invited as a founder member
2004: The Korean Society for Free Radical Research as a key note lecture speaker
2004: International Travel Grant by Biophysical Society, USA

代表論文:
  1. Hsiao CW, Peng TI, Peng AC., Reiter RJ, Tanaka M, Lai YK and Jou MJ*. Long-term Aβ exposure augments mCa2+-independent mROS-mediated depletion of cardiolipin for the shift of a lethal transient mitochondrial permeability transition to its permanent mode in NARP cybrids: a protective targeting of melatonin. J. Pineal Res. 2013, 54:107-125.
  2. Peng TI, Hsiao CW, Reiter RJ, Tanaka M, Lai YK and Jou MJ*. mtDNA T8993G mutation-induced mitochondrial complex V inhibition augments cardiolipin-dependent alterations in mitochondrial dynamics during oxidative, Ca2+ and lipid insults in NARP cybrids: a potential therapeutic target for melatonin. J. Pineal Res. 2012, 52(1):93-106.
  3. Jou MJ*. Pathophysiological and pharmacological implications of mitochondria-targeted reactive oxygen species generation in astrocytes. Adv. Drug Deliv. Rev. 2008, 60(13-14):1512-1526.
  4. Jou MJ*, Peng TI, Yu PZ, Jou SB, Reiter RJ, Chen JY, Wu HY and Hsu LF.  Melatonin protects against common deletion of mitochondrial DNA-augmented mitochondrial oxidative stress and apoptosis. J. Pineal Res. 2007, 43(4):389-403.
  5. Jou MJ*, Peng TI, Reiter RJ, Jou SB, Wu HY, and Wen ST. Visualization of the antioxidative effects of melatonin at the mitochondrial level during oxidative stress-induced apoptosis of rat brain astrocytes. J. Pineal Res. 2004, 37(1):55-70.

所有論文著作一覽表

學會與認證:
> Reviewer for Seicntific Journals:
Journal of Molecular Histology (USA)
Life Science (USA)
Acta Pharmacological (China)
Molecular Brain Research (USA)
Society for Free Radical Biology and Medicine (USA)
Journal of Pineal Research (USA)
FEBS letter (Federation of European Biochemical Societies) Review Editor of Frontiers in Genetics of Aging. (invited by Professor Henry Markram, president of Frontiers Research Foundation)
The Natural Products Journal (invited by Prof. Atta-ur-Rahman, FRS, chief editor of Natural Products Journal )
Journal of Biochemical and Pharmacological Research (invited by Prof. Liang -Jun Yan, chief editor of Journal of Biochemical and Pharmacological Research )
Review Editor of Frontiers in Genetics of Aging (invited by Professor Elena G. Pasyukova, Guest Associate Editor, Frontiers in Genetics of Aging)
PLOS ONE
BBA (Biochimica et Biophysica Acta)

> Memberships :
Biophysical Society, USA
Free Radical Biology and Medicine, USA
Mitochondria Research Society, USA
Nanomedicine, USA
Oxygen Club of California, USA (on the advisory board)
AAAS and Science, USA