陳怡原 ,Ph.D.
單位: 長庚大學
現職: 生物醫學研究所 微生物與免疫學科 教授
聯絡地址: 33302 桃園市龜山區文化一路259號
電話: 03-2118800 分機:3352
E-mail: mchen@mail.cgu.edu.tw
研究領域:- 微生物
- 醫學之生化及分子生物
工作經歷:2012-迄今 長庚大學生物醫學研究所及微生物免疫學科 教授
2004-2012 長庚大學生物醫學研究所及微生物免疫學科 副教授
2001-2004 Research Professor, Department of Oral Biology, University of Florida, Gainesville, Florida, USA
1995-2001 Research Assistant Professor, Department of Microbiology and Immunology, Center for Oral Biology, University of Rochester, Rochester, New York, USA
學歷:Ph.D., Microbiology, University of Texas Health Science Center, San Antonio, Texas, USA (1988-1993)
M.S., Microbiology, University of Georgia, Athens, Georgia, USA (1985-1987)
B.S., Biology, Fu-Jen Catholic University, Taipei, Taiwan (1980-1984)
代表論文:- S-C. Huang, R. A. Burne and Y. M. Chen*. 2014. The pH-dependent expression of the urease operon in Streptococcus salivarius is mediated by CodY. Appl. Environ. Microbiol. 80: 5386-5393. (SCI)
- Y. M. Chen*, H-R. Shieh, and Y-C. Chang. 2013. The expression of the fim operon is crucial for the survival of Streptococcus parasanguinis FW213 within macrophages but not acid tolerance. PLos ONE 8: e66163 (SCI)
- J. Geng, S-C. Huang, S. Li, S. Hu, Y. M. Chen*. 2011. Complete Genome Sequence of the ureolytic Streptococcus salivarius strain 57.I. J. Bacteriol. 193:5596-5597. (SCI)
- Y. M. Chen*, H-R. Shieh, C-T. Lin, and S-Y. Liang. 2011. Properties and construction of pFW213, a shuttle vector with the oral Streptococcus origin of replication. Appl. Environ. Microbiol. 77:3967-3974. (SCI)
- P-M. Chen#, Y. M. Chen #, S-L. Yu, S. Sher, C-H. Lai, and J-S. Chia. 2010. Role of GlnR in acid-mediated repression of genes encoding proteins involved in glutamine and glutamate metabolism in Streptococcus mutans. Appl. Environ. Microbiol. 76:2478–2486. (SCI)
所有論文著作一覽表
目前進行中研究計畫:2014/01/01-2016/12/31
Molecular and functional analysis of the type IV pili in Streptococcus sanguinis SK36 血鏈球菌SK36第四型纖毛基因群表現調控及功能之分析
2013/08/01-2016/07/31
Identification and characterization of the FimR regulon in the pathogenesis of Streptococcus parasanguinis 副嗜血鏈球菌FimR regulon之鑑定及功能解析