專業人才 > 免疫 | 感染醫學 | 風濕醫學 | 醫學之生化及分子生物

顧正崙 , Ph.D.
單位: 長庚大學
現職: 臨床醫學研究所 專任 助理教授
聯絡地址: 桃園市龜山區文化一路259號
電話: 03-2118800 分機: 3483(Office) 3496(Lab)
E-mail:clku@cgu.edu.tw

研究領域:
  • 免疫
  • 感染醫學
  • 風濕醫學
  • 醫學之生化及分子生物
研究成果:
  1. Host factors of severe mycobacterial and pyogenic bacterial infection.
  2. Molecular Mechanism of Anti-IFN-gamma Autoantibodies Disease in Patients with Non- tuberculous Mycobacterial Infection.
  3. Role of Innate Immunity Against Enterovirus infection in human.

工作經歷:
  》2010/08-迄今 長庚大學 助理教授
  》2008/08-2010/07 中國醫藥大學 助理教授

學歷:
  》巴黎第五大學博士

殊榮:
  • 2001 Ph.D fellowship from the French ministry of foreign affairs (2001)
  • 2013 Keystone Symposia Global Health Travel Award, funding by Bill & Melinda Gates Foundation.

代表論文:(*: first, co-first or corresponding author)
  1. Chi CY, Chu CC, Liu JP, Lin CH, Ho MW, Lo WJ, Lin PC, Chen HJ, Chou CH, Feng JY, Fung CP, Sher YP, Li CY, Wang JH & *Ku CL. Anti-IFN-gamma autoantibodies in adults with disseminated nontuberculous mycobacterial infections are associated with HLA-DRB1*16:02 and HLA-DQB1*05:02 and the reactivation of latent varicella-zoster virus infection. Blood. 2013, 121: 1357-1366.
  2. von Bernuth H, Picard C, Jin Z, Pankla R, Xiao H, Ku CL, Chrabieh M, Mustapha IB, Ghandil P, Camcioglu Y, Vasconcelos J, Sirvent N, Guedes M, Vitor AB, Herrero-Mata MJ, Arostegui JI, Rodrigo C, Alsina L, Ruiz-Ortiz E, Juan M, Fortuny C, Yague J, Anton J, Pascal M, Chang HH, Janniere L, Rose Y, Garty BZ, Chapel H, Issekutz A, Marodi L, Rodriguez-Gallego C, Banchereau J, Abel L, Li X, Chaussabel D, Puel A & Casanova JL. Pyogenic bacterial infections in humans with MyD88 deficiency. Science. 2008, 321: 691-696.
  3. Ku CL, von Bernuth H, Picard C, Zhang SY, Chang HH, Yang K, Chrabieh M, Issekutz AC, Cunningham CK, Gallin J, Holland SM, Roifman C, Ehl S, Smart J, Tang M, Barrat FJ, Levy O, McDonald D, Day-Good NK, Miller R, Takada H, Hara T, Al-Hajjar S, Al-Ghonaium A, Speert D, Sanlaville D, Li X, Geissmann F, Vivier E, Marodi L, Garty BZ, Chapel H, Rodriguez-Gallego C, Bossuyt X, Abel L, Puel A & Casanova JL. Selective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity. J. Exp. Med. 2007, 204: 2407-2422.
  4. von Bernuth H, Ku CL*, Rodriguez-Gallego C, Zhang S, Garty BZ, Marodi L, Chapel H, Chrabieh M, Miller RL, Picard C, Puel A & Casanova JL. A fast procedure for the detection of defects in Toll-like receptor signaling. Pediatrics. 2006, 118: 2498-2503. (co-first author and corresponding author)
  5. Ku CL, Yang K, Bustamante J, Puel A, von Bernuth H, Santos OF, Lawrence T, Chang HH, Al-Mousa H, Picard C & Casanova JL. Inherited disorders of human Toll-like receptor signaling: immunological implications. Immunol. Rev. 2005, 203: 10-20.


所有論文著作一覽表

目前進行中研究計畫:
  》2014/01-2015/12 抗丙型干擾素自身抗體(類愛滋病)之人類白血球組織抗原分析